Short answer: usually no — it depends on the type of VPN. Bixberry needs a real, everyday internet connection to work. Here's why, and what that means if you use a VPN.
Bixberry works on real internet connections, not ones routed through a data center. Most VPNs route your traffic through servers in data centers, and Bixberry can't run while one of these is active. A small number of VPNs work differently and route through everyday connections instead — Bixberry can run normally on those.
Best setup for earnings
Run Bixberry on your normal home or trusted Wi-Fi, with no VPN active. This is the simplest way to guarantee it runs.
With a typical VPN Most VPN services route through data centers. Bixberry will pause or fail to connect while one of these is active.
With some VPNs A small number of VPN providers route through everyday connections instead of data centers. Bixberry can run normally on these, though this is uncommon
If you rely on a VPN
Turn off your VPN while using Bixberry, and turn it back on afterward for your other activity.
If you need a VPN running at all times, Bixberry won't be able to run on that device — consider running it on a different device that doesn't need one.
If Bixberry isn't running or won't connect, check whether a VPN is active first. For more on what affects earnings, see How to increase your earnings.